Zainteresowania

• peptides
• binding
• receptor binding
• receptors
• opioid receptors
• amino acids
• peptide synthesis
• opioid peptides
• mass spectrometry
• docking

Dyscyplina naukowa

• nauki chemiczne

Najnowsze publikacje

• Synthesis and pharmacological evaluation of hybrids targeting opioid and neurokinin receptors.
• Endomorphin-2 analogs containing modified tyrosines: Biological and theoretical investigation of the influence on conformation and pharmacological profile.
• Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors
• Analgesic Peptides: From Natural Diversity to Rational Design
• Synthesis, pharmacological evaluation, and computational studies of cyclic opioid peptidomimetics containing β3-lysine
• Pharmacological characterization of µ-opioid receptor agonists with biased G protein or β-arrestin signaling, and computational study of conformational changes during receptor activation.
• Design, synthesis and functional analysis of cyclic opioid peptides with Dmt-Tic pharmacophore.
• Pharmacological profile and molecular modeling of cyclic opioid analogues incorporating various phenylalanine derivatives.
• Argireline: needle‐free botox as analytical challenge.
• Neuroprotective and Anti-inflammatory Effects of Rubiscolin-6 Analogs with Proline Surrogates in Position 2
• The 5-azoniaspiro[4.4]nonyl group for improved MS peptide analysis : a novel non-fragmenting ionization tag for mass spectrometric sensitive sequencing of peptides.
• Preparation of novel deuterated cyclosporin A standards for quantitative LC-MS analysis.
• Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues.
• Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold.
• Synthesis and activity of opioid peptidomimetics with β²- and β³-amino acids.
• Veni, Vidi, Vici: immobilized peptide-based conjugates as tools for capture, analysis, and transformation.
• Synthesis, receptor binding studies, optical spectroscopic and in silico structural characterization of morphiceptin analogs with cis-4-amino-L-proline residues.
• Citius, Altius, Fortius—Advanced Mass Spectrometry in Service of Forensic Analysis
• Spektrometria mas w analizie białek i peptydów : znaczniki jonizacyjne = Mass spectrometry in analysis of peptides and proteins : ionization markers.
• Chemical and biological properties of anti-wrinkle peptide Argireline = Argirelina - peptyd przeciwzmarszczkowy : właściwości chemiczne i biologiczne.